Lay media put emphasis on stem cell (SC) therapy has generally focused on two areas:
1. The promise of embryonic SC
2. The proliferation of charlatans preying to dreams and fears affiliated helpless patients.
While embryonic SC, in theory, appear to potentially be the ideal option for tissue regrowth, the hype has exceeded anticipation. Because of political and ethical concerns, research efforts with your cells has been unsatisfactory.
At the same time, news articles and television commentaries have in addition dealt with controversial parts of SC therapy. An inordinate amount of time has been devoted if you need to exposing the seamy football team... individuals involved in obvious hucksterism, the possible punishment of SC therapy and by practitioners, as well be the implication that all SC research conducted outside informative centers is suspect.
As a result of, there has been neglect regarding of an fascinating and promising associated with, particularly in arthritis comfort.
One of the increased intriguing studies was recently authored by Korean investigators (Pak M. Regeneration of human joints in hip osteonecrosis and all human cartilage in back osteoarthritis with autologous adipose-derived conclusion result cells: a case display. J Med Case Information. 2011; 7: 296)
The Mandarin chinese physicians treated four patients. Two (a 29 years old woman and a 47 yr old man) had osteonecrosis of their hip. Two other patients (a 70 years old woman and a 79 yr old man) had osteoarthritis of their knee. They were all given a wide selection of autologous stem cells (the person's own stem cells) derived from fat along with platelet affluent plasma, hyaluronic acid, nanogram amounts dexamethasone, and calcium chloride.
Pre and post rehabilitation MRI scans were present in all subjects. In the issue of patients with osteonecrosis, new bone formation was determined. In the patients installing osteoarthritis, new cartilage style was seen.
Along throughout the MRI findings, both fuzy pain measures and adaptive enough outcomes improved.
I found these findings to extremely interesting for a variety of reasons.
First, the mixture used as they Korean report is actually the one that everyone use at our heart, with one exception. The exception may be the: In addition to any certain SC, we also have got bone marrow derived stem cells.
And, while our center has taken excellent results with leg osteoarthritis (more than 90 nought per cent success), our experience with both hip osteoarthritis extremely hip osteonecrosis has chatted disappointing.
Why the distinction between hip and knee? I suspect it's because the mechanical forces changeable. The anatomy of any hip joint allows extreme rotation for several knee joint which is mainly a hinge joint with just a tiny rotation and some gliding. Activity level and body weight is likewise contributing factors.
Nonetheless, this report from Korea underscores what we believe really was... the use of autologous stem cells, also known signifies repair stem cells, will happen to be a fruitful area in the middle progress in osteoarthritis research for for future assignments.
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